Probiotics fight Cancer

Did you know that those bacteria in your gut (gastrointestinal system) plays a crucial role in the fight against a disease whose very name evokes fear--cancer. Yes, those bacteria squirming inside your intestines! So they better be good!

Probiotics fights Cancer
Probiotics fight Cancer

@healthbiztips by Arlene Gentallan

Probiotic is a widely researched topic. Of it's many health benefits, it's potent efficacy against cancer has gained considerable attention. It's quite amazing to think that those microbes living in our entrails affects us in a profound way.

A study by Li and colleagues uncovered that the oral probiotic mixture Prohep decreases the growth of liver cancer (hepatocellular carcinoma) by up to 40% in mice. Oral intake of probiotic is even more effective when taken as a preventive measure against cancer.

Probiotics are live microorganisms that gives benefits to our body. 

Did you know that inflammation promotes growth of cancer cells and creation of new blood vessel to support it's rapid growth. Probiotics counteract this by producing anti-inflammatory substances.


Probiotics does a number of health benefits to fight cancer:
  • Reduces gastrointestinal inflammation.
  • Reduces the blood supply of tumor cells, thus hindering tumor growth.
  • Prevents collonization of harmful bacteria.
  • Corrects the gut microbiota imbalance caused by cancer.
  • Inactivates carcinogenic and toxic substances
  • Boosts the body's immune system
  • Prevents many types of cancer like colorectal, cervical, liver, and bladder cancer.

What you eat impacts Gut Microbiota

The development of colorectal cancer is strongly linked to diet, particularly too much consumption of red meat and animal fat. What you eat reflects on your over all health and significantly impacts the microbial inhabitant of the gut which has recently been shown to actually play a role in the development of colon cancer.

For example, when you eat red meat, your body digests it and produces sulfur as one of the byproducts. High sulfur level is unfavorable for good bacteria, but it is provides a friendly environment for bad bacteria that produces carcinogenic compounds.
Probiotics or good bacteria are found throughout our body, not just in our gut. Your body is home to more than 100 trillion good bacteria. Now, that is a staggering amount of residents in just one body.

Probotics:
  • Antioxidant property
  • Reduces serum cholesterol
  • Helps digest food
  • Aids in the synthesis of Vitamins B and K
  • Prevents gastrointestinal infection

Probiotic aids people with:
  • Lactose intolerance
  • Gastroenteritis
  • Antibiotic-induced diarrhea
  • Constipation
  • Urinary tract infections
  • Inflammatory bowel disease
  • Irritable bowel syndrome
  • Allergy

Among the most popular probiotics are:
  • Lactobacillus acidophilus
  • Lactobacillus casei
  • Bifidobacterium breve
  • Bifidobacterium infantis
  • Bifidobacterium longum
  • Streptococcus thermophilus

How to get Probiotics?

Natural sources of probiotics (good bacteria) includes fermented products like:
  • Yogurt with live culture
  • Miso
  • Nato
  • Kimchi
  • Sauerkraut
  • Probiotic supplement

Know this:

If you are undergoing cancer treatment, don't hesitate to ask your doctor about taking probiotic supplement to explore the pros and cons as well as possible interaction with your current therapy. While probiotic can be used concurrently with cancer treatment, it's use remains a hot topic. Cancer therapy often cause patients to become immunocompromised or have a weak immune system which intake of probiotics can complicate by introducing live microorganism into the system at this time when the person  have an increased risk of developing sepsis.


Related articles:


Health Benefits of Probiotics
8 Ways "good" bacteria works to your advantage

Resources:

Li, J., Sung, C. Y. J., Lee, N., Ni, Y., Pihlajamäki, J., Panagiotou, G., & El-Nezami, H. (2016). Probiotics modulated gut microbiota suppresses hepatocellular carcinoma growth in mice. Proceedings of the National Academy of Sciences of the United States of America, 113(9), E1306?E1315. http://doi.org/10.1073/pnas.1518189113

Uccello, M., Malaguarnera, G., et al. (2012). Potential role of probiotics on colorectal cancer prevention. BMC Surgery, 12(Suppl 1), S35. http://doi.org/10.1186/1471-2482-12-S1-S35

Ciernikova, S., Mego, M., et al. (2017). Probiotic Survey in Cancer Patients Treated in the Outpatient Department in a Comprehensive Cancer Center. Integrative Cancer Therapies. 2017, Vol. 16(2) 188–195. DOI: 10.1177/1534735416643828

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Azcárate-Peril, M. A., Sikes, M., & Bruno-Bárcena, J. M. (2011). The intestinal microbiota, gastrointestinal environment and colorectal cancer: a putative role for probiotics in prevention of colorectal cancer. American Journal of Physiology - Gastrointestinal and Liver Physiology, 301(3), G401?G424. http://doi.org/10.1152/ajpgi.00110.2011

Liu, Z., Liu, W., Ran, C., Hu, J., & Zhou, Z. (2016). Abrupt suspension of probiotics administration may increase host pathogen susceptibility by inducing gut dysbiosis. Scientific Reports, 6, 23214. http://doi.org/10.1038/srep23214

Yang, Y., Xia, Y., Chen, H., Hong, L., Feng, J., Yang, J., Ma, Y. (2016). The effect of perioperative probiotics treatment for colorectal cancer: short-term outcomes of a randomized controlled trial. Oncotarget, 7(7), 8432?8440. http://doi.org/10.18632/oncotarget.7045

Caselli, M., Cassol, F., Calò, G., Holton, J., Zuliani, G., & Gasbarrini, A. (2013). Actual concept of probiotics: Is it more functional to science or business? World Journal of Gastroenterology: WJG, 19(10), 1527?1540. http://doi.org/10.3748/wjg.v19.i10.1527

Ho, Y.-H., Lu, Y.-C., Chang, H.-C., Lee, S.-Y., Tsai, M.-F., Huang, Y.-T., & Hsu, T.-Y. (2014). Daily Intake of Probiotics with High IFN-/IL-10 Ratio Increases the Cytotoxicity of Human Natural Killer Cells: A Personalized Probiotic Approach. Journal of Immunology Research, 2014, 721505. http://doi.org/10.1155/2014/721505

Sharma, M., & Shukla, G. (2016). Metabiotics: One Step ahead of Probiotics; an Insight into Mechanisms Involved in Anticancerous Effect in Colorectal Cancer. Frontiers in Microbiology, 7, 1940. http://doi.org/10.3389/fmicb.2016.01940

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