What is the difference between COX-1 and COX-2?

What is the difference between Cyclooxygenase-1 (COX-1) and Cyclooxygenase-2 (COX-2)?

by: Arlene Gentallan

Cyclooxygenase (COX) is an enzyme that plays a key role in the formation of prostanoids such as prostaglandins, prostacyclin and thromboxane--which are involve in inflammatory response (pain, swelling, redness, increase heat, and loss of function.) Prostaglandins are formed from arachidonic acid.


What is the difference between COX-1 and COX-2?


Cyclooxygenase-1 (COX-1):

        Presence in the body: It is produced at a constant rate by the body for it's normal functioning.

        Purpose: 

  • Regulates gastric acidity
  • Protects the gastrointestinal mucosa
  • Regulates water secretion by the kidneys
  • Blood clotting.
  • COX-1 is involve in the production of prostaglandin that is essential for the everyday functioning.

        Location: Predominantly found in the stomach, kidneys, and platelets.



Cyclooxygenase-2 (COX-2):

        Presence in the body: Not usually present in the body unless triggered by the immune system.

        Purpose: Responsible for the production of prostaglandin which is involve in inflammation, pain, and fever.

        Location: Commonly located at macrophages, leukocytes and fibroblasts at the site of inflammation.



SUMMARY:
Cyclooxygenase-1 (COX-1) is important to maintain the function of body organs such as stomach, kidneys, and platelet; while Cyclooxygenase-2 (COX-2) is primarily involve with inflammation and pain.


Sleep Deprivation accelerates Atherosclerosis - Healthbiztips

Lack of Enough Sleep puts you at risk of Heart Disease Don't underestimate the risks you're taking when you're not getting eno...

Labels

@healthbiztips (149) 10 Health Facts & Tips (15) absolute silence (1) acne (1) allergy (1) alternative medicine (10) anesthesia (1) anger (1) anti-aging (12) anti-epileptic (1) anticonvulsive (1) antioxidant (8) appetite (1) arthritis (34) asthma (2) asthma facts (1) athlete (1) babies (1) baby (1) Beauty product review (1) beauty secrets (33) blood donation (1) blood doping (1) blood doping in athletes (1) boredom (1) brain (2) brain facts (2) caffeine (2) calories (2) cancer (12) cancer treatment (1) cannabis (1) caterpillar fungus (1) cellphone (1) cellulite (1) cheating (1) child (1) children (1) chiropractic (1) chiropractors (1) cholesterol (2) clostridium tetani (2) coffee (5) coffee loco (5) coffee lovers (5) cold shock (1) cold shock response (1) cold water response (1) common cold (1) common cold facts (1) complementary and alternative medicine (2) compulsive liar (1) Corticosteroid (1) corticosteroid for kawasaki disease (1) cosmetic review (1) cough (1) Daily Health Tips (9) Daily Health Tips & Trivia (26) dementia (1) dental (1) depression (1) diabetes (2) diabetes mellitus (2) dietary supplement (1) dieting (8) diseases (50) dog (1) drug (3) drug guide (5) face mask (1) facts (3) facts about (1) facts about asthma (1) fats (2) fight stress (1) first aid (1) food allergy (1) food choices (4) food supplement (1) fruit (2) fruits (1) garlic (1) garlic oil (1) general anesthesia (1) gout (24) green tea (1) Haalthbiztips (1) hair health (1) hair loss (1) headache (1) health benefits (2) health blog (237) health breakthrough (1) health facts (1) health facts and tips (49) health hazards (26) health nlog (1) health questions (5) healthbiztips (120) height (1) herbal (3) high blood pressure (2) home remedies (38) home remedy (2) home vacation (1) how to wear (1) how to wear face mask (1) how to wear surgical mask (1) hypertension (2) immune system (1) immunity (1) inflammation (1) insomnia (3) Inspiring Motivational Quotes (7) intelligence (1) interesting reads (18) Interesting stuffs tips & quotes (48) Interesting Things (24) iq (1) is it safe (1) japan (1) japan health care (1) japanese (1) japanese health care (1) joint pain (1) kawasaki disease (3) kawasaki disease facts (1) keto diet (3) ketogenic diet (3) kitchen remedies (2) langsat (1) lansones (2) lanzones (2) lifestyle (1) liver (1) liver regeneration (1) localized tetanus (1) marijuana (1) measles (1) measles virus (1) medical breakthrough (1) medicine (1) milk (1) Motherhood (1) nap (1) natural remedy (12) neonatal seizure (1) newborn (1) nurses (10) oatmeal (1) Ophiocordyceps sinensis (1) osteoarthritis (9) pain (1) pedia (1) pet (1) pets and stress (1) phenytoin (1) physical activity (1) pimples (1) pregnancy (2) red wine (1) root canal (1) seizure (3) silence (1) skin care (12) skincare (1) sleep (4) sneeze (1) stress (2) stress management (3) superfood (1) superfoods (49) surgical face mask (1) surgical mask (1) tetanus (2) toothache (1) urinary tract infection (1) uti (1) vacation (1) vaccines (5) varicose viens (1) vitamin c (2) vitamins (2) vitamins boosts immune system (1) walkiing (1) weight gain (1) Weight Loss (8) Weight Loss Tips (13) zits (1)

Labels

@healthbiztips (149) 10 Health Facts & Tips (15) absolute silence (1) acne (1) allergy (1) alternative medicine (10) anesthesia (1) anger (1) anti-aging (12) anti-epileptic (1) anticonvulsive (1) antioxidant (8) appetite (1) arthritis (34) asthma (2) asthma facts (1) atherosclerosis sleep (1) athlete (1) babies (1) baby (1) Beauty product review (1) beauty secrets (33) blood donation (1) blood doping (1) blood doping in athletes (1) boredom (1) brain (2) brain facts (2) caffeine (2) calories (2) cancer (12) cancer treatment (1) cannabis (1) caterpillar fungus (1) cellphone (1) cellulite (1) cheating (1) child (1) children (1) chiropractic (1) chiropractors (1) cholesterol (2) clostridium tetani (2) coffee (5) coffee loco (5) coffee lovers (5) cold shock (1) cold shock response (1) cold water response (1) common cold (1) common cold facts (1) complementary and alternative medicine (2) compulsive liar (1) Corticosteroid (1) corticosteroid for kawasaki disease (1) cosmetic review (1) cough (1) Daily Health Tips (9) Daily Health Tips & Trivia (26) dementia (1) dental (1) depression (1) diabetes (2) diabetes mellitus (2) dietary supplement (1) dieting (8) diseases (50) dog (1) drug (3) drug guide (5) face mask (1) facts (3) facts about (1) facts about asthma (1) fats (2) fight stress (1) first aid (1) food allergy (1) food choices (4) food supplement (1) fruit (2) fruits (1) garlic (1) garlic oil (1) general anesthesia (1) gout (24) green tea (1) Haalthbiztips (1) haematopoiesis (1) hair health (1) hair loss (1) headache (1) health benefits (2) health blog (237) health breakthrough (1) health facts (1) health facts and tips (49) health hazards (26) health nlog (1) health questions (5) healthbiztips (120) heart (1) height (1) herbal (3) high blood pressure (2) home remedies (38) home remedy (2) home vacation (1) how to wear (1) how to wear face mask (1) how to wear surgical mask (1) hypertension (2) immune system (1) immunity (1) inflammation (1) insomnia (3) Inspiring Motivational Quotes (7) intelligence (1) interesting reads (18) Interesting stuffs tips & quotes (48) Interesting Things (24) iq (1) is it safe (1) japan (1) japan health care (1) japanese (1) japanese health care (1) joint pain (1) kawasaki disease (3) kawasaki disease facts (1) keto diet (3) ketogenic diet (3) kitchen remedies (2) langsat (1) lansones (2) lanzones (2) lifestyle (1) liver (1) liver regeneration (1) localized tetanus (1) marijuana (1) measles (1) measles virus (1) medical breakthrough (1) medicine (1) milk (1) Motherhood (1) nap (1) natural remedy (12) neonatal seizure (1) newborn (1) nurses (10) oatmeal (1) Ophiocordyceps sinensis (1) osteoarthritis (9) pain (1) pedia (1) pet (1) pets and stress (1) phenytoin (1) physical activity (1) pimples (1) pregnancy (2) red wine (1) root canal (1) seizure (3) silence (1) skin care (12) skincare (1) sleep (4) sneeze (1) stress (2) stress management (3) superfood (1) superfoods (49) surgical face mask (1) surgical mask (1) tetanus (2) toothache (1) urinary tract infection (1) uti (1) vacation (1) vaccines (5) varicose viens (1) vitamin c (2) vitamins (2) vitamins boosts immune system (1) walkiing (1) weight gain (1) Weight Loss (8) Weight Loss Tips (13) zits (1)